Posted by roscopeeco on January 9, 2011, at 18:36:53
In reply to Re: Tramadol for TRD » roscopeeco, posted by ed_uk2010 on January 9, 2011, at 14:24:31
> >How many people do you know that use suboxone as a recreational drug. It has naloxone in it as well.
>
> Sublingual buprenorphine was a popular recreational drug in Scotland back when Temgesic was more widely prescribed.
>
> I am aware that Suboxone contains naloxone, but that is only relevant when it is injected, it does not prevent dependence occurring with other routes of administration.
>
> >Try crushing it up and putting in your body by IV. See what happens.
>
> I'm not sure that comment was appropriate.
>
> I'm not trying to say that buprenorphine doesn't have a role in TRD. What I'm saying is that if you or anyone else thinks that it is somehow exempt from addiction and dependence issues, they are wrong.
>We are talking about TRD. Who cares about dependence. Have you reconciled the fact that TRD is going to need antidepressants for life. Isn't that a dependence as well. With cessation there are physical withdrawal symptoms as with a drug like suboxone. I don't get some people on this board. If the alternative therapy, that could actually help some, is "outside of the box" it is shot down just because of the qualities of dependence and addiction. Scare tactics aren't needed for people in search of freedom from a life of depression. The correct dosing in depression is under 2mg and not everyone becomes addicted nor has significant withdrawal symptoms from that dose. I am sure phillipa was talking about people who were on doses at 8 to 16mg with a prior opiate addiction. I am not addressing you in general. There is more supporting evidence that it can treat people with a fair percentage with TRD then the contrary. To not mention all possible therapies on a board like this is counterintuitive.
poster:roscopeeco
thread:975288
URL: http://www.dr-bob.org/babble/20101231/msgs/976364.html