Posted by merpmerp on January 3, 2011, at 10:24:35
The questions about TCAs are just because I'm curious about them; the questions about Wellbutrin are because I'm considering asking my doc about it.
I know very, very little about TCAs so please bear with me if the questions are ignorant :)
-Many TCAs work on both serotonin and norepinephrine. So how do they differ in mechanism from Effexor, Pristiq, Cymbalta, etc.?
-How do TCAs as a class differ in their subjective effects from SSRIs? (I mean I've read things like they are not often subject to 'poopout' and they work better for melancholic depression - which I have - than for atypical depression.)
-I keep reading conflicting things about Wellbutrin. Some sources say it works mainly on norepinephrine, other sources say it mainly works on dopamine. Which is it?
-If Wellbutrin affects dopamine, might it help with attention and motivation? (I'm struggling with this a lot but don't want to mess with Ritalin or Adderall.)
-Is Wellbutrin as often subject to nastiness like *s* ideation or 'poopout', which I've had with SSRIs?
Thank you.
Diagnosis: recurrent melancholic depression
Meds: Lexapro since Sept. 2009
poster:merpmerp
thread:975684
URL: http://www.dr-bob.org/babble/20101231/msgs/975684.html