Posted by bleauberry on December 23, 2010, at 7:59:40
In reply to cymbalta causing sadness and depression, posted by gatorlevi on December 22, 2010, at 19:47:55
> I have been on a plethora of anti-deppressants, 99% of which had no effects on me. The only one that worked was nardil and then it pooped out. I have tried cymbalta 3x, and each time it led me to have an overwhelming sadness with an increase in hopelessness and suicidal ideation. This occurred within 2-4 days of starting the medication, at regular dosage.(nothing like this happened with effexor) Any thoughts on what this might mean? on what might be beneficial??
> thanksWhat does this mean? Well, in my view it means you should probably stay far away from Cymbalta. Listen to what your body is telling you. It sounds like it is screaming NO.
Some people claim you have to go through a period of worsening before the med kicks in? I dunno about that. I sort of disagree with that being a sound strategy. Putting up with early side effects is one thing, but putting up with a worsening of the condition is a different beast.
All meds and herbs that are intended to improve mood can sometimes do the opposite. So it's important to pay attention to that. They don't put suicidal warnings on antidepressant labels for no reason.
Hidden from clinical studies are details that happened during the study. For example the suicides. They happen and are not generally made public. Obviously. Sheds a bad light on the pharm company, the drug, the researchers, and the FDA. It is always blamed on the depression not the drug. Of course, they didn't commit suicide before taking the drug, so go figure that kind of defensive logic.
This drug has been a miracle for some people. Others react very badly. All meds are like that.
Personally I found tiny amounts of cymbalta rather helpful, but higher amounts felt like dark death. My best dose was in the 10 beads per day range (the beads inside each capsule....10 of them is about 1mg). If I hit 5mg (50 beads) it felt really bad. But just a smidgen felt good.
If you want a true mix of serotonin/norepinephrine, it won't be found in cymbalta. Even if it was, you couldn't adjust the ratio. A much better bet than cymbalta would be to combine whatever SSRI you had that was most agreeable, and a TCA such as Nortriptyline.
And keep in mind it may not be any antidepressant that gets you feeling better. It is not unusual that something else will do it....mood stabilizer, antipsychotic, benzo, stimulant, herb, supplement, antibiotic, food choices.
If all those antidepressants failed you, that itself is your body trying to tell you something. Just listen.
poster:bleauberry
thread:974323
URL: http://www.dr-bob.org/babble/20101218/msgs/974409.html