Posted by Joe Schmoe on November 11, 2010, at 14:19:38
Since I suffer from social anxiety I have always had an interest in Nardil, supposedly the "gold standard" for SA. It sounds like it has severe weight gain and sexual side effects for many people though.
I was reading about it and apparently it raises the levels of dopamine as well as serotonin. This confused me, since I was also just reading about Vilazodone (with great hope) and it is supposed to not have sexual side effects, because its effect on the 5-HT1a autoreceptor somehow causes dopamine release. Similarly, Wellbutrin is often used to help with ssri sexual side effects because of its dopamine raising effect. I have often read that sexual disfunction caused by ssri's is due to their tendancy to suppress dopamine.
If Nardil raises dopamine levels and not just serotonin, why does it still have sexual side effects?
poster:Joe Schmoe
thread:969787
URL: http://www.dr-bob.org/babble/20101107/msgs/969787.html