Posted by Tomatheus on November 8, 2010, at 11:57:00
In reply to Question for those who've tried MAOIs, posted by Conundrum on November 8, 2010, at 11:17:51
Conundrum,
When MAOIs worked for me, they alleviated all of my symptoms, including anhedonia. For as long as I benefited therapeutically from MAOIs, I never felt numb, flat, or empty on them. When Nardil worked, it was about as effective on my anhedonia as Parnate and Marplan were when they worked. The biggest problem that I had with MAOIs (which is the same problem that I've had with most antidepressant treatments) is that they didn't keep working. Both Marplan and the version of tranylcypromine manufactured by Goldshield brought my symptoms into remission for about three days and then just about completely stopped working. Film-coated Nardil brought my symptoms into remission for about two weeks, the Australian Nardil brought my symptoms into remission for about a month when taken in enteric capsules, and Pfizer's Nardil brought about a robust antidepressant response for about two months when I took it in enteric capsules. Of course, not everybody is going to have the same problems with MAOIs that I had. Some patients actually seem to be able to get a consistent response out of them, and my guess is that the medications' effectiveness in treating anhedonia will vary from person to person. It'll be interesting to see what others have to say.
Tomatheus
Diagnosed with schizoaffective disorder. Currently taking 5 mg Abilify, 12.5 mg Lamictal, 2.25 mg Hydergine, and four supplements.
poster:Tomatheus
thread:969189
URL: http://www.dr-bob.org/babble/20101107/msgs/969201.html