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Metoclopramide + Promethazine - antipsychotics?

Posted by jerryTRD on November 7, 2010, at 20:43:11

Metoclopramide (Reglan) is used to help with gastric motility and nausea. Promethazine (Phenergan) is an old antihistamine that is used for nausea and vomiting and sedation. But what I noticed about both is that they both antagonize dopamine receptors and carry warnings of EPS & Tardive Dyskinesia.

For you self-taught pharmacologists out there - are these two meds old cousins of antipsychotics?

Just curious

Jerry

Major Depressive Disorder, treatment-resistant w/GAD. Meds: Lexapro 10mg, Adderall IR 20mg 3x daily, Klonopin 1mg 5x daily, Seroquel 300mg, Ambien 10mg, Synthroid 125mcg, Androgel

 

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poster:jerryTRD thread:969050
URL: http://www.dr-bob.org/babble/20101107/msgs/969050.html