Posted by linkadge on October 21, 2010, at 20:13:43
In reply to Re: Going from Zoloft to Remeron I am worried :(, posted by morgan miller on October 19, 2010, at 20:46:10
>One of the reasons why they made Lexapro was >because of the greatly reduced amount of side >effects.
They didn't really "make" lexapro. Escitalopram has been around for about 25 years as a metabolite of citalopram. It was not "designed" to have less side effects, this is simply the result of having less drug in your system. Some people have more side effects (i.e. anxiety, activation) with escitalpram vs. citalopram.
>The other reason was because it simply worked >better.
This is a matter of debate. All of the studies suggesting superiority of escitalopram were funded by lundbeck when citalopram came off patent. If the theory regarding citalopram is true, it would have more serotonergic side effects, due to absence of the metabolite which counteracts serotonergic effects.
poster:linkadge
thread:966136
URL: http://www.dr-bob.org/babble/20101020/msgs/966517.html