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Re: Low dose Geodon stimulating / insomnia?? » displaced9

Posted by SLS on October 20, 2010, at 5:58:26

In reply to Low dose Geodon stimulating / insomnia??, posted by displaced9 on October 19, 2010, at 22:22:31

> Hi, I was recently (about 2.5 weeks ago) switched from Seroquel XR 100MG @ 6pm to Geodon. We started at 20mg of Geodon,

With Geodon, 20mg can cause agitation and insomnia. At 40mg, these things disappear in most cases. For depression, it is often not necessary to go higher than between 40mg and 80mg. This pattern is supposed to occur as the result of a predominance of 5-HT2c blockade at lower dosages, and the emergence of dopamine D2 receptor blockade and perhaps 5-HT1a stimulation at higher dosages.


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