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Re: why no relief from anxiety with clomipramine?

Posted by Brainbeard on October 15, 2010, at 6:54:45

In reply to why no relief from anxiety with clomipramine?, posted by g_g_g_unit on October 15, 2010, at 6:06:05

That's why my doc adds fluvoxamine: to reverse the SRI/NRI ratio. Normally, blood levels of the NRI metabolite dominate over blood levels of the SRI motherdrug. When fluvoxamine is added, the mother drug is boosted while the metabolite is suppressed. He finds this an excellent combo for OCD.

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Current meds: clomipramine 225mg, fluvoxamine (Luvox) 50mg
As needed: bethanechol 25-50mg, oxazepam 5-10mg

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poster:Brainbeard thread:964485
URL: http://www.dr-bob.org/babble/20101009/msgs/965805.html