Posted by linkadge on September 20, 2010, at 18:16:25
In reply to Lou's request-micheigh, posted by Lou Pilder on September 20, 2010, at 15:23:06
Methylphenidate can actually protect dopamine cells from certain dopaminergic neurotoxins.
For instance, pretreatment of brain cells with ritalin appears to block some of the damaging effects of MPTP a potent neurotoxin capabile of producing parkinsons like effects.
Amphetamine may be more associated with catecholamine depletion, but this has only been shown conclusively at high doses.
The other issue is that parkinsons is not due to dopamine depletion per se, it is due to neurodestruction of dopamine producing and recieving cells. You depleat brain stores of dopamine and produce parkinsonian like symtpoms, but this is not parkinsons disease.
Linkadge
poster:linkadge
thread:963143
URL: http://www.dr-bob.org/babble/20100917/msgs/963168.html