Posted by bleauberry on August 31, 2010, at 15:15:33
In reply to Reboxetine/Edronax, posted by atypical on August 29, 2010, at 23:36:22
In pbabble world this med hasn't worked out anywhere near as good as clinical trials would suggest. Makes one kind of wonder about the accuracy of those trials.
My own belief is that no NRI is likely to provide lasting relief.
I think the key is to have both sri and nri at the same time. Clomipramine is probably the only TCA that fits that description but side effects are kind of stiff.
Dr Gillman favored combos such as zoloft+nortriptyline or zoloft+reboxetine. Zoloft was the typical choice due to the fewest interactions or liver complications during combinations. The overall idea is....both norepinephrine and serotonin at the same time...not just one or the other. That said, in a combination it might work well. By itself, my gut instinct says no.
poster:bleauberry
thread:960569
URL: http://www.dr-bob.org/babble/20100829/msgs/960833.html