Posted by bleauberry on August 13, 2010, at 19:03:00
In reply to Milnacipran Experiences, posted by a_nicholson1980 on August 10, 2010, at 2:18:43
I guess my overall message about milnacipran is that since it has displayed the ability to normalize longterm adrenal, thyroid, and immune problems with longerm treatment, it impacts a lot of stuff in the body. And since we don't know all those details within our own illnesses and bodies, it makes sense to approach the whole thing with gentleness. Which to me means starting, and sometimes staying at, minimum doses. The multiple dosing is also extremely important. Studies with once daily dosing were no better than placebo. The halflife is only 8 hours.
And I can't help but repeat, there are few monotherapy meds that can show improvement when someone fails ECT. But milnacipran did that to me, and I've read about it a couple other times at other forums. I don't see those same kinds of stories with things like lexapro, cymbalta, or effexor. And to think, it was a mere 6mg taken twice a day that blew ECT in the weeds? I mean, ya know, come on, there is potential there. I've seen people fail on milnacipran too, and they failed in clinical trials, so in that respect it is not the magic bullet. But certainly deserves a shot. With the exception of SLS, the failures I've seen here were either due to: too high of a dose; not frequent dosing; too quickly increasing dose; urination side effects; not trying common add-ons (ssri, zyprexa, risperdal).
The starter pack ramps up dose really fast. That's insane in my opinion. It should be literally 10 times slower than that. The people who wrote those instructions have obviously never ingested the drug themselves.
poster:bleauberry
thread:958128
URL: http://www.dr-bob.org/babble/20100811/msgs/958482.html