Posted by Highnote on August 12, 2010, at 21:32:56
In reply to Re: Switching From MAOI to another MAOI Wait Period?, posted by linkadge on August 12, 2010, at 18:51:41
> What is the theory behind the need for a washout from MAOI to MAOI?
>
> LinkadgeSide effects and lack of dose equivalency were good reasons in my case. I just switched from Nardil to Parnate after finding Nardil rather nasty. I could not have coped with their combined side effects and Nardil withdrawal during an equivalent-dose switch. Worse, "equivalent" doses aren't at least for me. One Parnate tablet affects me about as much as 3 Nardil. If I had tried to go straight from 3 Nardil to 3 Parnate...forget it.
Interestingly, according to the antidepressant comparison chart at www.rxfiles.ca, no washout is needed when switching between TCA's.
poster:Highnote
thread:958359
URL: http://www.dr-bob.org/babble/20100811/msgs/958399.html