Posted by Conundrum on July 15, 2010, at 23:21:24
I have been taking Mirtazapine since June 25. On June 29th I added prozac. On July 4 I noticed a big increase in my desire to play music. A few days later this went away. I know that feeling wasn't from prozac, since it doesn't work that soon or that well. Mirtazapine directly blocks some serotonergic receptors. Prozac indirectly activates those same receptors. Could it be that the opposing actions is what made the motivation from mirtazapine go away? Or is it that quick mirtazapine poop out? I have heard that it poops out fast like in a month or something. My pdoc said thats a good sign that it will work better later on at a higher dose. When the receptors down regulate from prozac will the drugs work better?
I'm wondering if I should have restarted prozac while starting mirtazapine. Maybe I should stop taking prozac and just stay at 30 mgs mirtazapine for awhile. Anyone have any ideas or experience with adding an SSRI to mirtazapine in that order?
I'm not sure if I should stay on the prozac and increase the mirtazapine later, or just let the prozac leave my system and then increase the mirtazapine, so I know what is doing what.
Post-SSRI syndrome: iatrogenic anhedonia, memory and concentration problems, sexual dysfunction. [NOTE no sadness or anxiety]
Location:USA
Currently taking 300mg Lamictal and 30mg mirtazapine.
poster:Conundrum
thread:954637
URL: http://www.dr-bob.org/babble/20100709/msgs/954637.html