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why do antipsychotics work faster than antideps?

Posted by inanimate peanut on July 4, 2010, at 18:53:56

If most of the antipsychotics work on 5HT receptors similar to most SSRIs in addition to the other work they do on D receptors, etc., why do antipsychotics work so much faster than antidepressants? Maybe their non-5HT effects work more quickly and then the 5HT action follows on later, but if that is the case then their efficacy should improve around weeks 4-6, which doesn't seem to be the case. Also, I've been told that I only need to trial APs for 2 weeks whereas anti-depressants trial for 4-6 weeks. Does anyone have any clue why this is the case?


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poster:inanimate peanut thread:953307
URL: http://www.dr-bob.org/babble/20100628/msgs/953307.html