TC-5214...future hope for depression??

Posted by rovers95 on June 20, 2010, at 17:01:35

Below is a link regarding AstraZeneca's TC-5214, which is being proposed for release in 2013 (all being well) as an augmentor for antidepressants when patients fail the initial trial, it has shown promising results in this respect so far and as someone who subscribes to the cholinergic theory of depression i believe/hope it may benefit myself and many others.
http://www.news-medical.net/news/20100420/AstraZenecaTargacepts-TC-5214-for-treatment-resistant-depression-to-earn-Decision-Resources-gold-standard-status.aspx
there's plenty of stuff out there on this drug, such as.
http://www.medicalnewstoday.com/articles/157831.php
Unlike scopolamine, which i responded to briefly but then went into cholinergic overdrive since i believe that TC-5214 is a non-competitive antagonist of nicotinic receptors. Will this mechanism of antagonism prevent the up-regulation of nicotinic receptors that hinders long term success with current nicotinic antagonists?
Also, i don't really understand what it takes to get a new drug onto the market so is anyone able to shed any light on the probability of this drug making it into production?
thanks
rover

Thread

TC-5214...future hope for depression?? rovers95 6/20/10
Re: TC-5214...future hope for depression?? » rovers95 SLS 6/20/10
Re: TC-5214...future hope for depression?? Bob 6/22/10
Re: TC-5214...chances of getting to market?? rovers95 6/22/10
Re: TC-5214...chances of getting to market?? linkadge 6/25/10
Re: TC-5214...future hope for depression?? » Bob Conundrum 6/27/10
Re: TC-5214...chances of getting to market?? » linkadge rovers95 6/27/10

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