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Re: Starting Milnacipran

Posted by vic80 on May 16, 2010, at 11:57:58

In reply to Re: Starting Milnacipran, posted by bleauberry on May 15, 2010, at 20:47:41

Hi Bleauberry,

Thanks for your inputs regarding Milnacipran.

firstly, theres no doubt that diff people react diff to meds, the mileage may vary etc etc, but how would you rate your experience over all?
How long did you take/ are taking MIL?
and if you stopped what was the reason behind it?

I have noticed tachycardia - pulse hasnt been below 96 since I started yesterday. And also I have found that I get a sense of uneasy calm - head-feels-blocked sort of calm - and theres increased irritability too.
I have noticed an elevation in my confidence in social situations and for the first time in months, just for a few minutes I could actually feel involved emotionlly in a social gathering without that 'invisible veil' thing.
(But that could be the 0.5 mg lorazepam I had taken a 15 mins before.)

Over all it reminds me a bit of Remeron (caused me to have hypertension and severe anhedonia in just 10 days, not to mention the Movie-star dreams which was kind of fun come to think of it)

I have Depersonalization symptoms too but are either iatrogenic (started in 2nd week lex) or comorbid with depression. OCD (mainly O) too has exacerbated DP symptoms.

would you know of any positive results in DP, assuming you must have researched into MIL while on it! I have been unusually unsuccessful with googling about it.

I think as you have pointed out apathy caused by high serotonin could also be because I am taking lexapro 7.5 mg (plus the build up of several weeks in my system) which is a seriously potent serotonin RI. The combined effect of MIL and Lex on Serotonin RI must be a cause of the mental deadness i felt.

I am a bit apprehensive about the mood and confidence elevation I have felt even though subtle in the past 2 days - it has been too sudden and feels a bit false. I guess Lex taper/withdrawal too could induce mild hypomania.

Did you experience any mood swings/hypomania or irritability on MIL?

With a lot of difficulty I have reconciled to the fact that psychoactives arent a smooth ride after all but I am pinning a lot of hope on MIL.


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poster:vic80 thread:947505
URL: http://www.dr-bob.org/babble/20100514/msgs/947600.html