Posted by bulldog2 on May 2, 2010, at 17:52:00
In reply to Re: Just took hydrocodone(percocet)... » bulldog2, posted by ed_uk2010 on May 2, 2010, at 17:00:23
> >I don't agree that mood improvement is only several weeks.
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> I suppose that the duration is variable. If an opioid was used to treat depression, it seems unlikely that any improvement would be sustained in the long term. I do recognise that opioids have a role in the treatment of certain types of chronic non-cancer pain, however.
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>Well we do know that heroin addicts are maintained on methadone for years. Apparently it sustains their mood enough to keep them off heroin. Wether it is an antidepressant is open to debate.
The fact that people make their own internal endorphins that sustain mood seems to suggest the possibility of doing this with a synthetic drug. We know some p-docs are beginning to play around with bup. Opiates,opioids, seem to be part of the depression puzzle for many.
The synthetic drugs available may not be the answer. But it needs to be pursued as it appears some are depressed because of a shortage of these endorphins. What we now have does eventually poop out because the body recognizes them as foreign and finds ways to get them out of the body.So as with synthetic hgh we need to duplicate these endorphins so the body does not recognize them as invaders.
poster:bulldog2
thread:945983
URL: http://www.dr-bob.org/babble/20100425/msgs/946017.html