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Re: Whats the effect of Benzodiazepines on Dopamine etc?

Posted by linkadge on April 30, 2010, at 13:39:41

In reply to Re: Whats the effect of Benzodiazepines on Dopamine etc? » whymelord, posted by Phillipa on April 30, 2010, at 13:27:36

Its completex. Some of the benzos have direct opioid binding effects (like xanax).

I think they can cause a release of dopamine in the neucleus accumbens but gaba-a agonists can degrease dopamine release in certain limbic regions too. Doctors have noted that in certain cases of schizophrenia, benzo's can treat acute flare ups as well as antipsychotics. And benzos like clonazepam have documented antimanic effects. I think the benzo's can induce a sense of well being, possibly due to effects on the opiate system, but its not the same kind of euphoria that stimulants give - i.e. massive power trip dopamine rush.

To answer your question. I dunno.

Linkadge


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