Posted by bulldog2 on April 25, 2010, at 13:45:26
In reply to Re: Clomipramine and Tachycaridia? » hopefullynow, posted by conundrum on April 25, 2010, at 12:41:03
> Nice, I'm looking for something for anhedonia and the TCAs keep looking better and better. Not to knit pick but i think remeron and buspar are actually decreasing serotonergic transmittion rather than increasing it. Remeron is blocking those "bad" receptors and buspar tells the brain to stop producing as much serotonin for a little while and both increase noradrenaline and dopamine release.
If you like the effects of serotonin than clomipramine is the way to go.At only 50 mg it has a calming effect reminiscent of an ssri. Also add in a moderately strong ne effect and you have a well balanced ad. At 50 mg I find the sides very tolerable. I realize that some have to go up to 200 mg where I guess the sides could be bad.But there is evidence that tcas might work as well at low doses as high doses. If clomipramine is to much serotonin than you have imipramine which is a very balanced se and ne ad.
I guess see if they work for you at 100 mg or under where sides might be very tolerable.
poster:bulldog2
thread:944867
URL: http://www.dr-bob.org/babble/20100425/msgs/945031.html