Posted by bulldog2 on April 21, 2010, at 15:40:16
In reply to Re: Clomipramine » SLS, posted by Justherself54 on April 21, 2010, at 12:37:33
> Hi Scott.
>
> From what I understand from my pdoc is the range for depression treatment is between 100 and 200 mg. I was to have a blood test two weeks after increasing it to 100 mg. to test the levels. We both thought I was on 75 mg and was tolerating it quite well, although my depressive symptoms are still pretty bad, but I know now I'm still at 50 mg.
>
> The other 3 TCA's I've tried were amitriptaline, nortriptaline, and one other (the name escapes me right now). All caused such severe sedation to the point where I was sleeping during the day for more than 10 hours, and was not hearing the telephone ring, nor my dog barking. When I was awake I felt like I was hungover.
>
> I have three small grandchildren and I was afraid I wouldn't respond during that kind of sleep if something happened when they were staying with me.
>
> I have to say I was not thrilled to try another TCA, due to my previous experiences with them, however, this is so different, it gives me hope that I can get some relief from the depression.
>
> Right now all I'm experiencing as side effects are dry mouth, loss of appetite (OK by me as I'm overweight) and more difficulty sleeping and a bit of sedation during the day, but not enough to even have a nap on.
>
> That's why I'm wondering if I could tolerate the increase to 100 instead of doing the 75 mg increase, just to try to quickly reach a more theraputic range for my depressive symptoms, but I also want to be cautious not to invite a host of unwelcome side effects by doing it too quickly.
>
> Thanks so much for your response.
>I would do the 75 just to make the transition smoother. You'll get to 100 quick enough. So this is a tca that requires a certain blood level to be effective?
I'm up to 50 mg and I didn't get any sciatica relief. A little disappointed. I thought 50 mg was the lowest dose for a therapeutic response but I guess I was wrong.
poster:bulldog2
thread:944260
URL: http://www.dr-bob.org/babble/20100416/msgs/944389.html