Posted by conundrum on March 24, 2010, at 23:26:33
In reply to Re: Severe anhedonia...I can't live like this anym, posted by Economist on March 24, 2010, at 21:46:43
I would seriously consider trying a tricyclic like nortriptyline, vivactil, or desipramine. The nice thing is they seem to work faster than drugs that work on serotonin.
If you have given your dopaminergic regimen enough time its probably time to move on to a new strategy.
Think of anhedonia like this. You have cable tv. There is the cable company sending you the signal, thats the stimulus. Then there is the wire connecting to the cable company to your house. Thats serotonin, then there is norepinephrine which is the converter box that goes to your tv. Then your TV is dopamine. If any thing goes wrong with any of those parts your image won't be clear. Your first guess might be to blame the TV(dopamine), but it could be your box or the cables to and from the box. Its not as simple as low dopamine being the cause for anhedonia all the time for every person.
Check out the abstract link below. I would have posted it but some of the symbols displayed wrong in the preview mode.
Noradrenaline is necessary for the hedonic properties of addictive drugs
poster:conundrum
thread:940577
URL: http://www.dr-bob.org/babble/20100318/msgs/940745.html