Posted by desolationrower on March 3, 2010, at 1:53:32
In reply to Re: Seroquel and Nardil, posted by GreenP on February 24, 2010, at 17:11:57
> Hi Courtney,
>
> I am not a doctor, but the reason for the 2 week "wash out" period is because SSRIs up the amount of serotonin and other chemicals in your body chemistry.
> "Seroquel is thought to be an antagonist for two primary neurotransmitters (chemicals in the brain), serotonin and dopamine." (Rusk, 2009)
> For this reason, seroquil might cause might cause serotonin syndrome when used with an MAOI. And in order for seroquil to not interact with the new MAOI you are trying, you have to be off of it for two weeks. So my advice would be to proceed with caution.
>
> You can also check drug interactions here:
> http://www.drugs.com/drug_interactions.html
>
> Hope this was helpful and good luck to you!
>
> Citation:
> 1. The Effects of Seroquel on Serotonin
> http://www.ehow.com/facts_5533435_effects-seroquel-serotonin.html
> Author: Sara M. Rusk
> Posted: 2009
> Retrieved: Feb 24, 2010quetiapine & norquetiapine have little afinity for the sert and any increase in 5ht is from alpha2 antagonism, and the 5ht antagonism would prevent 5ht syndrome from happening, though not as well as risperdal or something.
see http://www.dovepress.com/getfile.php?fileID=5763, http://kidb.cwru.edu/pdsp.php
-d/r
poster:desolationrower
thread:885671
URL: http://www.dr-bob.org/babble/20100216/msgs/938425.html