Posted by Brainbeard on February 25, 2010, at 3:30:28
In reply to Re: New combo - Debating CAN Be Constructive, posted by sigismund on February 24, 2010, at 20:32:08
> Perhaps you do get used to the antihistamine effect?
>
> When I tried it I took 25mg and was so wrecked the next day I never repeated it.Oh yes, you can become tolerant to the antihistaminergic effect. I also took 25mg of amitriptyline the first time and was an irritable zombie the next day.
Then I started anew with 6mg, going up in steps of 6mg. That worked fine. With every raise in dose, I would be a little more irritable than I normally am, but that would last only a day.
I have currently worked my way up again to 50mg of amitriptyline, without much trouble. I don't experience much sedation, while I also take 2400mg of Neurontin. I've taken larger steps this time, of approximately 10mg every one or two days, and I encountered no problems except for the mentioned temporary irritability.
poster:Brainbeard
thread:937465
URL: http://www.dr-bob.org/babble/20100216/msgs/937849.html