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Re: Diphenhydramine HCL and MAOIs - Any Reactions?

Posted by Tony P on January 30, 2010, at 18:27:42

In reply to Re: Diphenhydramine HCL and MAOIs - Any Reactions?, posted by inanimate peanut on January 18, 2010, at 10:35:14

I took DPH with Selegeline (EMSAM etc.) with no problem. I have no experience or knowledge of the interaction with the older MAOI's. BTW, I tried Cyproheptadine as well and found it was _longer_ lasting than DPH but gave a more natural sleep.

*** WARNING: MAOI's can be deadly with Dextromethorphan (cough-suppressant) & very dangerous with some oral decongestants (phenylephrine seems to be OK, Sudafed is an absolute NO). I would avoid taking brand-name products such as Benadryl, especially liquids, which are often combinations with the above. Look for plain diphenhdramine tablets, which are cheaper anyway.


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