Posted by Brainbeard on January 27, 2010, at 8:22:38
In reply to Re: Prozac dosage questions » Brainbeard, posted by KarenRB53 on January 26, 2010, at 18:40:39
> What is your opinion on Cymbalta or Pristiq, they're both SNRI's aren't they? In your opinion would the TCA's be a better way to go than the Cymbalta or Pristiq?
Both Cymbalta and Pristiq are likely to have horrible withdrawal syndromes.
Cymbalta (generic name duloxetine) doesn't seem to be much special, it may lack some of the typical side-effects of TCA's (dry mouth, constipation, cognitive debilitation, cardiac burden) but it has its own bizarre list of potential side-effects. It may be a good choice for some people who are both depressed an in pain.
Pristiq, which is practically identical to Effexor (generic name venlafaxine), is in its own league. Some people get chronically happy on it. It seems to be a unique drug, even thoug its pharmacological profile doesn't seem all that unique. Trouble is, you might never get off it or get off it and be in greater misery than when you started. (Of course the latter is a problem with all SSRI's too.)
So yeah, I would be more inclined to try TCA's first and see how well you can tolerate them and how well they work. If you go TCA, build doses up slow to avoid premature disappointment because of the side-effects. TCA's have some incovenient side-effects, but they have a lot to offer.
Oh my... Off-topic.
poster:Brainbeard
thread:904045
URL: http://www.dr-bob.org/babble/20100122/msgs/935124.html