Posted by MoonageDaydream on January 23, 2010, at 15:25:42
In reply to EMSAM IS AN ASTOUNDING RIPOFF, posted by aminated on January 22, 2010, at 17:47:13
The Emsam patch has 74% bioavailability and keeps selegeline levels steady, whereas the pill has 4% bioavailability and peaks and troughs. What this means is you get WAY more selegeline in your system with Emsam. If you take the pill, much more is metabolized into l-methamphetamine, which basically just causes side effects. Emsam allows for selegeline levels that inhibit both MAO-B and MAO-A, and for a lot of people, MAO-A inhibition is necessary for any antidepressant response. By being a patch it avoids the necessity of dietary restrictions.
If I didn't have insurance, though, I'd almost certainly go for selegeline in the tablet form, because Emsam is ridiculously expensive.
poster:MoonageDaydream
thread:933399
URL: http://www.dr-bob.org/babble/20100122/msgs/934794.html