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Re: Zonisamide/Zonegren

Posted by willey on January 16, 2010, at 11:56:08

In reply to Re: Zonisamide/Zonegren » willey, posted by SLS on January 16, 2010, at 5:46:44

Here scott,i was informed by two people,pre informed sadly,one by a babble,and one out left field in a general chat which was eerie.,I posted this in the first place because it is not mentioned much in zonegrans initial data sheet info.

Heres a snip from the first article,

"Reports of zonisamide-associated behavioral deterioration and psychotic episodes are increasing.[14, 15] The frequency of psychosis is higher than that reported for epilepsy-associated psychosis. In addition, none of our patients had demonstrated behavioral disturbances or psychotic behavior before receiving zonisamide therapy

These actions, as well as increases in dopamine transmission, may demonstrate zonisamide's multiple modes of action related to hallucination pathogenesis"


http://www.medscape.com/viewarticle/448287_3

http://www.ncbi.nlm.nih.gov/pubmed/8991786

http://www.biopsychiatry.com/zonisamide.htm


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