Posted by West on January 16, 2010, at 4:41:55
In reply to Re: switching from venlafaxine/mirtazap to moclobe, posted by europerep on January 10, 2010, at 10:37:11
Hi, This is a late reply as well. I hope you're still feeling a bit more positive like you said.
I should avoid duloxetine since it's very tiring funnily enough, despite the binding profile. Keep us posted on the 600/60 combo, I would imagine you're getting enough NA action here (but watch out for hypertension and irritability.)
I mentioned academic difficulties since these can be extensions of other underlying attentional disorders, which can themselves cause depression and anxiety. But glad to hear you're doing well in class. Hope this continues.
W
> I actually wanted to go down on mirtazapine, so that I can add bupropion soon, the problem is that at 600 venlafaxine/30 mirtazapine, I started to have some trouble sleeping, i.e. I woke up early in the morning, with difficulties to fall asleep again, or waking up again just a couple of minutes later, and so on.. that is why I decided to go back to 600/60 for the moment, because right now I need to be preparing for the upcoming exams, and for that I really need to have a sound sleep.. plus I am a little better than when I originally started my thread, but still, I am far from being well.. I am still wondering whether I should increase mirtazapine, I might at least have a try at it, but personally I don't think that will be the solution, the improvement I felt when starting to take it, and when increasing dosages, was very minimal..
>
> Were you refering to duloxetine for example when you said that I might profit from a more equal targeting of NE and 5HT?
>
> as for the circumstances.. of course it would be too easy to say that all the problems I currently have are a mere result of the depression.. I have already done a psychotherapy, and I guess I will start another one, so I am certainly not rejecting this approach to improving my current state.. however, there are limits as to what that can do for me, especially in the sense that, the way I feel right now, it would be very, very difficult to introduce substantial changes into my life.. I don't expect a better medication scheme to solve my problems, but merely to get me to the point (where I was already, before effexor lost its effectiveness), where I am confident that I can actually do this..
> the difficulties with studying I was refering to are primarily a result of the inability to get up before noon or even later, which I experienced about a week ago.. now that is gone, and I am back to the situation I was used to, which is that I don't have trouble getting up, just that I need more sleep than others (eight to nine hours), in order to be able to study, concentrate, etc..
> as for the last question, I did not have academic difficulties before being depressed. in fact, I am still doing rather well in classes etc., but that does not reflect a general state of well-being..
>
> thanks for taking the time to read this!
poster:West
thread:930533
URL: http://www.dr-bob.org/babble/20100113/msgs/933895.html