Posted by Brainbeard on January 4, 2010, at 14:36:59
In reply to Prozac + elavil - I need reassurance!, posted by orbital on January 2, 2010, at 17:20:18
Lower dose Prozac with low dose Elavil (amitriptyline) is a fine combination.
Here's a handy study to give you an idea of Prozac's potentiation of amitriptyline: http://www.ncbi.nlm.nih.gov/pubmed/7751409
A regimen of 20mg of Prozac raises amitriptyline blood levels about twofold, but nortriptyline levels (the active metabolite) about ninefold.
I'm on 25mg of amitriptyline at the moment, and I've been taking small doses of Prozac (about 5mg a day) for a while.
Your doc has been perfectly cautious by setting the max at 25mg.
poster:Brainbeard
thread:932166
URL: http://www.dr-bob.org/babble/20100103/msgs/932465.html