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Re: Remeron + Paxil: so far, so good... or is it? » mtdewcmu

Posted by SLS on January 3, 2010, at 11:30:39

In reply to Re: Remeron + Paxil: so far, so good... or is it?, posted by mtdewcmu on January 3, 2010, at 8:57:01

> So 5-HT3 has a stimulatory effect. I may have remembered the table slightly incorrectly; it says that 5-HT3 causes release of 5-HT from enterochromaffin cells in the GI mucosa and it causes fast depolarization of enteric ganglion cells; 5-HT2A is listed as causing contraction of intestinal smooth muscle. 5-HT2B and 5-HT4 are listed as causing contraction of the stomach fundus and esophagus, respectively. So that would explain why mirtazapine has a greater relaxing effect on the bowel than ondansetron.
>
> Thanks for getting me to look that up and correct my memory.

Thanks for checking into it and reminding me that my memory is far from infallable.


- Scott

 

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