Posted by SLS on December 26, 2009, at 21:52:37
In reply to Seroquel made me bad...Why oh why?, posted by Phidippus on December 25, 2009, at 15:29:30
> Yesterday I took a 600 mg dose of Seroquel and felt fine for a couple hours, then BAM! I was hit with a severe fear sensation/dissociative moment then I freaked out and became very agitated. I spent the night in the ER. What the f*ck? Did Seroquel worsen my OCD?
You didn't just take 600mg of Seroquel as your first dosing of this drug, did you?
The major metabolite of Seroquel (quetiapine) is norquetiapine. Norquetiapine is a potent norepinephrine reuptake inhibitor, a property that can produce activation. This can serve to make some people irritable or hostile. It might make sense that there be a delay in the onset of your negative reaction if it is indeed the norquetiapine metabolite that is to blame.
- Scott
poster:SLS
thread:930874
URL: http://www.dr-bob.org/babble/20091217/msgs/931049.html