Posted by bleauberry on December 25, 2009, at 12:29:45
In reply to sertraline and nort., posted by gman22 on December 24, 2009, at 12:18:47
To answer a few questions, I agree with everyone else's comments here.
I found Nort to disturb my sleep the first 2 or 3 nights, definitely a higher NE thing and also I could sense some of that serotonin ssri insomnia thing, but it was all mild. Light sleep with several wakings. But after that, sleep was good. I developed an early morning waking, but slept good till then. I did not find Nort sedating in a way that it would knock me out at bedtime.
Actually I found the best time for me to dose it was between 4pm and 6pm in the afternoon. Bedtime was much too late for me.
I started it with 6.25mg zoloft and was feeling decent benefits alredy by day 3. For some stupid reason someone convinced me to just go with the nort. I hate ssri's anyway and agreed. I think that was a mistake because over the next couple weeks I didn't gain any new ground and then lost everything I had gained. The zoloft was an integral part of the plan. I need to redo this.
Savella (Milnacipran), heavy on NE, gave me great sleep. It however had much more peripheral NE effect than Nort. I think Nort is mostly nervous system focused, but Savella goes everywhere pretty strong. Nort didn't give me any of the heavy NE urinary side effects that Savella did.
In any case, I think NE reuptake inhibition helps sleep, probably through feedback loops, while NE stimulation and release (stimulants, remeron..though smothered out by potent antihistamine) these things worsen sleep. I don't know, that's my crude way of describing my experience.
poster:bleauberry
thread:930705
URL: http://www.dr-bob.org/babble/20091217/msgs/930842.html