Posted by ace on December 24, 2009, at 17:38:19
In reply to Re: Help w/ atypical depression? (my first post here), posted by West on December 24, 2009, at 8:50:21
> 'Finally, another phenomenon I have CONSISTENTLY experienced is that when I come off SSRI's, I feel better for like a day or two.'
>
> All SSRIs are indirectly anticholinergic so you experienced cholinergic rebound, which feels good, (before you inevitably relapse into hellish depression).I have not heard of cholinergic rebound producing a good feeling. I have heard of it causing depersonalization problems, which, when not associated with phobic anxiety, could produce a relaxed, dreamy sensation.
I would also assume this applies to the shorter acting SSRI's
> Could be lessened REM sleep suppression making you feel better slept/more restored (like back in the day when you were young and unconflicted)What accounts for the lessened REM sleep again?
poster:ace
thread:930645
URL: http://www.dr-bob.org/babble/20091217/msgs/930751.html