Posted by casse on December 22, 2009, at 12:46:04
In reply to Re: LDN Low Dose Naltrexone Questions, posted by Jimmyboy on October 8, 2009, at 9:39:48
I'm new to this board and have been searching through older threads on LDN. I've been using it off and on since June '09. I can't take the 1.5 mg that is reported to be the minimally effective dose. In fact I just started back on it at .25mg every other night. Some people are so extremely sensitive to meds that they must start very low. Dr. Lawrence ( UK ) uses doses lower than 1.5 mg. for some of his patients.
I'm still fiddling with trying to find the right way to dose, but I'm not alone. There is a new yahoo group dedicated to people who are using very low dose naltrexone. I don't get the mental anxiety from it if I take too high a dose, I just feel ill at ease physically and that can be exhausting. But I feel that way anyway it's just a little worse with LDN sometimes. Overall, I feel that LDN is helpful. I can get out of bed and think more clearly. The initial icky feelings on it make me think "homeopathic" might be accurate in describing it's action.
I've done a lot of reading about Naltrexone, and one outstanding complaint in people on it at 25+ mg. is anxiety. Loss of pleasure is also common. I suspect that even at low doses it might sequester in tissue, resulting in constant blockade of endorphin production instead of the intermittent blockade that is therapeutic. That's why I skip doses. I'm still trying to find what works best.
I compound my own from 50mg tabs in syrup from the pharmacy to get such a low dose. 100ml of syrup ( or distilled water ) makes for .5mg pr 1 ml.
Are you still using it?
poster:casse
thread:919880
URL: http://www.dr-bob.org/babble/20091217/msgs/930336.html