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Re: Washout Period for MAOI - Celexa

Posted by SLS on December 21, 2009, at 14:41:21

In reply to Re: Washout Period for MAOI - Celexa » RSidney, posted by ace on December 17, 2009, at 6:20:24

> > I have been off EMSAM for 1-week, after being on it for 5 weeks, with only two of those weeks on 6mg/9mg.
> >
> > Is it possible/safe that I could go onto my next SSRI (Celexa) sooner than the two week wait?
> > I know the two weeks is "standard" but I can feel my serotonin drop from leaving the EMSAM and would like to start Celexa ASAP.
>
> Hi mate,
> I would not advise this...at all.
>
> I switched to Anafranil from nardil after around 16/17 days and had a pronounced 5HT syndrome.

It takes significantly longer for MAO activity to recover after Nardil discontinuation than for Parnate discontinuation. This is according to some rather old data, but some of the best work involving MAOIs took place in the 1970s and 1980s.


- Scott

 

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