Posted by bleauberry on December 20, 2009, at 21:01:46
In reply to Is there hope for Post SSRI side effects?, posted by conundrum on December 20, 2009, at 11:48:10
This phenomenon has been experienced by perhaps half a dozen people or more at this board over the last 6 months. We've kind of given it the name post-ssri syndrome. It can happen with all the ssris, not just prozac.
I think somehow over longterm the heavy serotonin manipulation causes adaptive changes on the other neurotransmitter systems and genes.
The best things I have found all include a fairly strong focus on norepinephrine, but with a little bit of serotonin too. Those include:
1. Nortriptyline+Zoloft (very low dose zoloft, such as 6mg or 12.5mg).
2. Milnacipran (Savella) low dose (12.5 bid or 25mg bid).
3. Parnate any dose from 5mg to 80mg.Wellbutrin or Remeron? No, forget it. For an ex longtime ssri user these will work lousy or worse.
Mileage varies of course.
poster:bleauberry
thread:929993
URL: http://www.dr-bob.org/babble/20091217/msgs/930068.html