Posted by SLS on November 26, 2009, at 8:07:42
In reply to Re: Lyrica and BZD discontinuation » SLS, posted by tensor on November 26, 2009, at 7:14:46
I know that both Trileptal and Lamictal block or stabilize voltage-gated sodium channels. However, where the two drugs differ is that Trileptal also potentiates GABA receptors. Trileptal also affects second messenger events. I don't think Lamictal does this.
It is important to note that Lamictal was developed and marketed as an add-on to other anticonvulsants. It was meant to combine with drugs like Trileptal. There is no reason why you could not combine them and take advantage of the mood-enhancing effect of Lamictal while taking Trileptal temporarily only during the time of BZD withdrawal.
I found Trileptal to have antidepressant properties. I experienced no side effects. The only caveat is that you need to be careful to check your electolytes every now and then. Trileptal can produce hyponatremia (too little sodium).
Perhaps you could start with the Trileptal and add Lamictal later if Trileptal is not adequately treating the depression.
- Scott
poster:SLS
thread:926916
URL: http://www.dr-bob.org/babble/20091117/msgs/927029.html