Posted by mtdewcmu on November 26, 2009, at 2:09:01
In reply to tramadol in a.m. or p.m., posted by meAgain on November 21, 2009, at 22:29:32
> I just started Tramadol for pain in my back. If I take in the early morning before I go to work will I get drowsy?
>
> Thanks guysTramadol is a unique drug. It inhibits the reuptake of norepinephrine and serotonin, and its active metabolite is an agonist at mu opioid receptors. So its effects are a combination of an opiate and something that feels vaguely like a tricyclic antidepressant. Depending on which effect wins out, you may feel activated or drowsy. I have taken it together with Celexa, and there was an unpleasant interaction, but mainly at higher doses (I felt restless and irritable). I think the combination slightly increases the risk of seizure. Be careful in that some people like the effects and, like an opiate, there is the potential for tolerance and withdrawal.
poster:mtdewcmu
thread:926493
URL: http://www.dr-bob.org/babble/20091117/msgs/927011.html