Posted by Dave954 on October 6, 2009, at 20:55:27
In reply to Re: Need advice for treatment resistant insomnia, posted by zzzz7 on October 5, 2009, at 21:49:53
Well, one of my concerns is that nothing is more sedating than Seroquel or Remeron (or the two combined which I have already tried) - my understanding is that the TCAs are actually less sedating comparatively speaking. I also understand that the TCAs have similar issues with daytime sedation and somnolence - which always aggravates my depression. I want to try something that has a high likelihood of working this time around. I fear that nothing may be sufficient enough to keep me asleep for 7 to 8 hours any longer. I am hoping Zyprexa might work or some special type of dosing schedule with a combination of things taken at bedtime and then again 4 hours later to keep me asleep (like I am currently doing with the Seroquel - I set my alarm clock to wake me 4 hours later to take more so that I can get barely enough sleep to function the next day - I have tried all the XR formulations with no success). I wish the medical community had a better understanding of neurology and insomnia treatments so that there were more options available for hard cases like me. There appears to be nothing of significance coming up in the pipeline - just more 'me too' drugs with similar mechanisms of action. I miss the days when just 200 mg of Seroquel gave me a guaranteed 8 hours of sleep a night...
poster:Dave954
thread:919704
URL: http://www.dr-bob.org/babble/20091001/msgs/920017.html