Posted by bleauberry on October 5, 2009, at 21:36:25
In reply to Re: cymbalt - long withdrawal » floatingbridge, posted by yxibow on October 5, 2009, at 0:37:36
Just a followup on comments about Savella.
I personally liked it. I mean, what could possibly work when ECT fails? Well for me that was Savella. Probably part of the Lyme complex, but my urinary stoppage was so severe I could not continue with Savella. Other than that, I am a fan.
I have seen at least two cases here that did not go well with Savella, just to keep it in perspective.
At another forum there were people who were actually in the clinical trials, a few of them on Savella for up to 12 months. The overall message from them was that even though there might be a hint of improvement in pain, fatigue, and depression, within a couple weeks, the real good stuff didn't start to happen until the 3 month mark. For one person it was 9 months, but he was so happy he stuck it out. I think Savella somehow causes longterm beneficial readaptations within complex systems involving the adrenals, thyroid, and immune system. It was not uncommon for people to feel more tired before feeling improvement, almost like a healing crisis of some kind.
To put withdrawals in perspective. My withdrawal from Savella after 4 weeks on it was about the same as the withdrawal from being on Cymbalta just 3 days. In other words, sure, I could tell it was an AD withdrawal, but it wasn't crippling and it was over in a couple days. I don't know why Savella is so tame in that regard while Cymbalta is so mean.
poster:bleauberry
thread:919574
URL: http://www.dr-bob.org/babble/20091001/msgs/919861.html