Posted by SLS on September 20, 2009, at 7:13:14
In reply to Re: Failed rilutek perhaps try memantine with Lamictal, posted by sam K on September 20, 2009, at 2:06:24
I think that combining memantine with lamotrigine is a great idea.
You can also try adding Topamax to create a three-pronged attack against glutamate hyperactiviety, as each drug works on different aspects of glutamatergic neurotransmission.
1. Lamictal (lamotrigine): glutamate release inhibitor
2. Namenda (memantine): NMDA glutamate receptor antagonist
3. Topamax (topiramate): AMPA/kainite glutamate receptor antagonist.
Lamictal sucks as an antimanic agent. Topamax is probably better for mania than Lamictal.
- Scott
poster:SLS
thread:917737
URL: http://www.dr-bob.org/babble/20090912/msgs/917772.html