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Re: question about Parnate insomnia » g_g_g_unit

Posted by SLS on September 11, 2009, at 0:35:58

In reply to question about Parnate insomnia, posted by g_g_g_unit on September 10, 2009, at 23:08:11

> i don't mean to seem impatient, and i know there are a lot of others in far worse situations here. but i would rather titrate and endure side-effects, than hang around needlessly at low doses. my psych assured me that it passes at his oft-used dose of 20mg, but my impression from browsing the archives is that higher doses are required

I think your doctor is doing you a disservice by targeting the dosage of Parnate at less than 40mg. Unfortunately, the silly manufacturer label calls for the following:

"Parnate Dosage and Administration

Dosage should be adjusted to the requirements of the individual patient. Improvement should be seen within 48 hours to 3 weeks after starting therapy.

The usual effective dosage is 30 mg per day, usually given in divided doses. If there are no signs of improvement after a reasonable period (up to 2 weeks), then the dosage may be increased in 10 mg per day increments at intervals of 1 to 3 weeks; the dosage range may be extended to a maximum of 60 mg per day from the usual 30 mg per day."

A more realistic dosing schedule would look like the following:

"Parnate Dosing for Depression
The recommended starting Parnate dose for depression is 30 mg per day (divided into two or three smaller doses during the day). If your depression does not improve in two weeks, your healthcare provider may slowly increase your dose up to a maximum of 60 mg per day."

http://depression.emedtv.com/parnate/parnate-dosage.html

For someone who is taking Parnate for the first time, it is prudent to start at 10mg for a few days, and then 20mg for a few days before moving up to 30mg.

I am trying to look for a more persuasive source of information that might indicate that dosages of 40-60mg are more realistic for Parnate treatment.


- Scott

 

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