Posted by SLS on August 27, 2009, at 7:00:45
In reply to AD that will get me out of bed, posted by morganator on August 27, 2009, at 0:21:58
> Hey Scott, What do you think of the idea of taking Parnate one time in upon waking and Agomelatine one time at night before bed?
I am really hoping that Parnate and agomelatine can be combined. I would like to try that for myself if things don't work out for me with lithium.
I can see how agomelatine might remain effective as a sleep enhancer, but I am not as sure that Parnate will remain effective as a promoter of wakefullness. I should think that the body would build up a tolerance to the amphetamine effect of Parnate. What about using Provigil? I would continue to dose Parnate in a twice a day manner. I still think going 24 hours without Parnate allows for too much MAO recovery. I really don't have a good "feel" for once a day dosing. With me, however, if I miss my afternoon dose, by early evening I can already feel the effects, often falling asleep and having vivid and hypnagogic dreaming, presumably a REM rebound effect. I never tried taking all of my Parnate at once, so I can't really attest to its utility.
- Scott
poster:SLS
thread:914302
URL: http://www.dr-bob.org/babble/20090826/msgs/914323.html