Posted by SLS on August 18, 2009, at 13:25:50
In reply to Re: my new Dx » floatingbridge, posted by SLS on August 18, 2009, at 6:02:21
> I don't know where I heard this, but I was once told that MAOIs can actually slow down the aging process. I'm not sure what was meant by that, though. Apoptosis perhaps?
Selegiline (-deprenyl; Emsam; Eldepryl) has long been recognized as being ant-apoptotic presumably through its influence on mitochondria function. However, someone told me about this anti-aging thing a long time ago referring to the older MAOIs. After doing some snooping on Medline, I was unable to find anything that would corroborate this.
MAOI-B activity accelerates with age, leading some investigators to theorize that it is this phenomenon that produces late-onset depression. Perhaps the older MAOIs prevent the excessive oxidative H2O2 (peroxide) that this enzyme would produce, thus slowing the aging process.
- Scott
poster:SLS
thread:912700
URL: http://www.dr-bob.org/babble/20090818/msgs/912835.html