Posted by Alexanderfromdenmark on August 10, 2009, at 22:16:33
In reply to Re: Popular Antidepressants: How They Stack Up » elanor roosevelt, posted by tensor on August 9, 2009, at 18:18:49
> > > I simply cannot bring myself to believe that mirtazepine is the most effective AD.
> > this seems unbelievable to me but in these studies meds that stupify you into submission come out looking great
> > >
> >
> >
>
> Obviously many hate Remeron, but none have suggested another AD as the most effective. I certainly hope it isn't because of meds have stupified you. ;-)
>
> /Mattias
I can easily see why Remeron could be the most effective antidepressant compared to the SSRI's.
First of all it makes you sleep! It's neigh impossible to stay sane without sleepIt's reduces cortisol, eg Adrenal output. This may be good or bad. But most depressives are heading for adrenal burnout or are already in it. By reducing adrenal output, it gives the adrenal glands a rest.
It decreases prolactin meaning that it increases sex drive and won't make you temporary or permenantly impotent like SSRI's.
Speaking from a man's perspective, it is pro-testosterone whereas 90% of avaible AD's are Anti-testosterone.
Not good for most men. Espcially depressives.
It increases dopamine in the prefrontal cortex. This is good for some reason.
It increases serotonin, but not by reuptake inhibition, This means that it dosn't lead to lower melatonin and other unhealthy stuff.
It stimulates appetite. This could be good or bad for some people. But I like that wolf-hunger feeling.
Increased NE can result in higher mood, more alertness. Too much can result in irritability and anxiety.
Long--term it looks like a better drug as it won't result in adrenal burnout or hypogonadism where as SSRI's can cause and do cause problems like these.
poster:Alexanderfromdenmark
thread:910431
URL: http://www.dr-bob.org/babble/20090810/msgs/911468.html