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Re: Mixed Hypomanic Episode + Medication Changes

Posted by SLS on August 6, 2009, at 7:44:38

In reply to Re: Mixed Hypomanic Episode + Medication Changes, posted by atypical on August 6, 2009, at 4:09:15

> There are also lots of other meds (Lamictal?) to consider. Of course, this all takes time. Ugh.

Lamictal is a great choice when an antidepressant effect is needed. However, it makes a poor anti-manic drug to be used acutely. It does make for a good combination with lithium, IF lithium were to treat the mania successfully. For right now, the fire must be put out, and the lithium doesn't seem to be helping. I would think drugs like Depakote would be indicated, perhaps using Zyprexa temporarily.

Just as a reminder, if Depakote and Lamictal are to be combined, the dosage of Lamictal must be cut in half. Depakote reduces the clearance of Lamictal by inhibiting glucuronidation.


- Scott

 

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