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Fluoxetine or venlafaxine?

Posted by tensor on August 4, 2009, at 13:23:29

My Lexapro trial is coming to an end. I have taken 20mg along with 30mg of Remeron for depression and panic attacks. The panic anxiety is under control but the depression is not lifting. Have no energy, no motivation or interest. I have to make a decision what to try next. I would like to try one newer antidepressants before resorting to TCAs (not that they are guaranteed to work.), it's either fluoxetine or venlafaxine as I can see.
I'm a bit confused over the noradrenergic properties of venlafaxine, but I guess at high enough dose it's there. Venlafaxine is possibly stronger, but as I can recall fluoxetine has a more favorable s/e profile. Oh, I'm keeping Remeron at 30mg.

Please come with ideas, or pros and cons.

Kind regards,
Mattias


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