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Re: SLS - what other TCA's have you tried?

Posted by linkadge on July 31, 2009, at 14:27:52

In reply to Re: SLS - what other TCA's have you tried? » linkadge, posted by SLS on July 31, 2009, at 6:25:07

Thanks for the inquiry. About 3 weeks ago I saw a good psychiatrist for the first time. He has been dealing with my mother and doing a good job.

I went to him while taking ritalin and sertraline. What you describe is almost identical to what I described to him. I said I am depressed for about a week (or a little longer) then feel ok for about 3 days or so. The main symptoms I have are feeling extremely fatiqued, somewhat worthless, with much anhedonia. I said the sertraline helped initially, but seemed to stop working. I said they tried higher doses in the hospital which always left me agitated. I also said I have zero sexual function on it.

We discussed nortriptyline since this recomendation was made by the previous psychiatrist. He told me to come off the sertraline for a month, see what happens then likely go with a nortriptyline trial.

I have one more week before I see him for this. The sertraline withdrawl has produced more anxiety than depression. Infact, my depression is about the exact same. The doctor mentioned that we might need to go to imipramine depending on the response to nortriptyline.

I am concerned about an imipramine trial becuase of the genotoxicity, but on the other hand I know it can be a very effective AD for some. I am hesitant to tell him about my concerns because traditionally my relationship with psychiatrists has soured when I start to express knowledge / concernes with specific recomendations.

I am willing to do a trial of nortriptyline or amitriptyline, but would like to avoid the others if at all possible.


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poster:linkadge thread:909310
URL: http://www.dr-bob.org/babble/20090721/msgs/909467.html