Posted by jerrypharmstudent on July 27, 2009, at 13:52:19
In reply to Re: Extreme internal restlessness/agitation!!!! HE » jerrypharmstudent, posted by linkadge on July 25, 2009, at 7:22:45
> Whether a TCA would completely cover what zyprexa does isn't 100% clear. There is overlap in the receptors that they hit.
>
> A number of doctors think that zyprexa (and other atypicals) augments SSRI's owing to its 5-ht2a/c receptor blockade and possibly its muscarinic receptor antagonism. Most TCA's share these effects (less so with imipramine and desipramine though).
>
> If depresson is the core issue, I think there is a good chance that something like nortriptyline or amitriptyline would have a similar (if not more possitive) effect but one cannot say for sure.
>
> Linkadge
>Saw my pdoc today and he instead wanted to try Geodon. I've gained 20 lbs from the Zyprexa in just 6 weeks. I had a good and very immediate response from Zyprexa so now I'm nervous to be switching. Anything you can tell me about Geodon?
Thanks
Jerry
poster:jerrypharmstudent
thread:908370
URL: http://www.dr-bob.org/babble/20090721/msgs/908837.html